The story revolves around Bhaskar, played by Varun Dhawan, who undergoes a transformation after being bitten by a wolf while on a trip to Arunachal Pradesh. As Bhaskar turns into a werewolf, he faces various challenges, including managing his dual identity and the chaos that ensues in his life.

The film blends elements of humor and horror, incorporating local folklore and showcasing the beauty of the northeastern region of India. With a mix of action, visual effects, and quirky characters, "Bhediya" explores themes of friendship, love, and the struggle for self-acceptance. The film also features Kriti Sanon and Abhishek Banerjee in pivotal roles, adding to its comedic and emotional depth.